January 25, 2012

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sarafem

As research and development costs have climbed, drug companies are more interested than ever in finding ways to repurpose their products. Often they seek to simply market an existing drug for a new condition, but in some cases they give the drug a whole new name and face.

When Eli Lilly's patent on Prozac (fluoxetine) expired in 2001, the company saw sales of the blockbuster drug plummet as the market opened up to competition from cheaper generic versions. In what some experts saw as a move to stem losses, Lilly began marketing fluoxetine for premenstrual dysphoric disorder, a severe form of PMS.

With the new use came a new brand: Sarafem. Pink-and-purple capsules in sunflower-bedecked packaging replaced the gender-neutral green and white of Prozac.

While studying a drug for heart-related chest pain in the 1990s, Pfizer researchers discovered that men who took it experienced a surprising side effect: erections. The drug proved ineffective for chest pain, but Viagra was born.

Pfizer later explored other uses for the drug, which relaxes blood vessels, and in 2005 the FDA approved it for pulmonary hypertension, under the brand name Revatio.

Learn more from MSN.

January 25, 2012

Latest Comments

  • drugs with multiple uses

    A comment about all the unapproved uses companies are trying to market drugs for would be pertinent. Since Pfizer had to pay 2.8 & 4 billion dollars in fines for this practice of marketing drugs for unapproved uses, this would fit with this current story.

    Posted by Mark January 26, 2012 13:26:23

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